Pharmacophore an International Research Journal
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Open Access | Published: 2020 - Issue 2

Role of IL-10 In Inhibition of Trichomonas Vaginalis Killing And IFN- Γ Activated Macrophages ‎‎ Download PDF

Noor Ibrahim Abdulzahra, Jasim Hameed. Taher, Raja Jawad Mohamed

This study was carried out to evaluate the cytokines profile, Interleukin-10 (IL-10), and Interferon-gamma (IFN-γ) in the serum of infected women using ELISA Techniques. The blood samples were collected from 64 women infected with Trichomonas vaginalis and suffering from vaginal discharge attending the outpatient clinics at Al-Zahra'a children and Maternity Hospital and private clinics, Najaf, between June 2016 to March 2017, in addition to 32 healthy patients as a control. Blood sera were obtained from those women. The cytokines IL-10 and IFN-γ were evaluated in serum. There was a significant increase in both cytokines in the infected women, and also both cytokines showed significant differences. These trichomoniasis patients showed higher production of IL-10 and lower IFN-γ, resulting in a higher ratio of IL-10: IFN-γ compared to the control group ratio.

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ISSN: 2229-5402

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